EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.1.1.3 | (R,S)-flurbiprofen ethyl ester + H2O |
enantioselective reaction |
Bacillus cereus C71 |
(S)-flurbiprofen ethyl ester + (R)-flurbiprofen + ethanol |
- |
? |
3.1.1.3 | (R,S)-flurbiprofen ethyl ester + H2O |
enantioselective hydrolysis, kinetic resolution, overview |
Serratia marcescens |
(S)-flurbiprofen + ethanol |
- |
? |
3.1.1.3 | (R,S)-flurbiprofen ethyl ester + H2O |
high enantiomeric excess and conversion yield of 98% and 48%, respectively |
Serratia marcescens |
(S)-flurbiprofen + ethanol |
- |
? |
3.1.1.3 | (R,S)-flurbiprofen ethyl ester + H2O |
enantioselective hydrolysis, kinetic resolution, overview |
Serratia marcescens ES-2 |
(S)-flurbiprofen + ethanol |
- |
? |
3.1.1.3 | (R,S)-ibuprofen + 1-propanol |
purified enzyme in a mixture of 1-propanol-isooctane in a ratio of 3:1, the conversion of racemic ibuprofen reaches 46% with very high enantioselectivity for production of the (S)-enantiomer |
Penicillium expansum |
(S)-ibuprofen n-propyl ester + (R)-ibuprofen |
- |
? |
3.1.1.3 | (R,S)-ibuprofen + 1-propanol |
purified enzyme in a mixture of 1-propanol-isooctane in a ratio of 3:1, the conversion of racemic ibuprofen reaches 46% with very high enantioselectivity for production of the (S)-enantiomer |
Penicillium expansum PED-03 |
(S)-ibuprofen n-propyl ester + (R)-ibuprofen |
- |
? |
3.1.1.3 | (R,S)-mandelonitrile + vinyl acetate |
transesterification |
Alcaligenes sp. |
(S)-cyano(phenyl)methyl acetate + (R)-mandelonitrite |
- |
? |
3.1.1.3 | (R,S)-naproxen 2,2,2-trifluoroethyl thioester |
(R,S)-profen 2,2,2-trifluoroethyl thioester |
Carica papaya |
(S)-naproxen + 2,2,2-trifluorothioethanol + (R)-naproxen 2,2,2-trifluoroethyl thioester |
- |
? |
3.1.1.3 | (R,S)-[4-[4a,6b(E)]]-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-hydroxy-2H-pyran-2-one + isopropenyl acetate |
- |
Burkholderia cepacia |
(R)-(+)-[4-[4a,6b(E)]]-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-hydroxy-2H-pyran-2-one + (S)-(-)-[4-[4a,6b(E)]]-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-acetyloxy-2H-pyran-2-one + prop-1-en-2-ol |
- |
? |
3.1.1.3 | (R/S)-ibuprofen methoxyethyl ester + H2O |
- |
Candida cyclindraceae |
(R)-ibuprofen methoxyethyl ester + (S)-ibuprofen + 2-methoxyethanol |
- |
? |