EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.14.20.13 | more |
the enzyme also catalyzes the reaaction of EC 1.14.11.11 |
Atropa belladonna |
? |
- |
? |
| 1.14.20.13 | more |
enzyme catalyzes both the hydroxylation of hyoscyamine, reaction of EC 1.14.11.11, and the epoxidation of 6beta-hydroxyhyoscyamine to generate scopolamine |
Anisodus tanguticus |
? |
- |
? |
| 1.14.20.13 | more |
enzyme catalyzes both the hydroxylation of hyoscyamine, reaction of EC 1.14.11.11, and the epoxidation of 6beta-hydroxyhyoscyamine to generate scopolamine |
Hyoscyamus niger |
? |
- |
? |
| 1.14.20.13 | more |
enzyme catalyzes both the hydroxylation of hyoscyamine, reaction of EC 1.14.11.11, and the epoxidation of 6beta-hydroxyhyoscyamine to generate scopolamine. Epoxidase activity is low compared to the hydroxylase activity. The binding of the substrates, hyoscyamine and 2-oxoglutarate, to the enzyme induces significant conformational changes |
Datura metel |
? |
- |
? |
| 1.14.20.13 | more |
enzyme is able to catalyze hydroxylation, dehydrogenation and in vitro epoxidation reactions all giving scopolamine. Hydroxyl rebound is unlikely to take place during the cyclization reaction and the hydroxylase versus oxidative cyclase activity is correlated with the presence of an exo-hydroxy group having syn-periplanar geometry with respect to the adjacent H atom to be abstracted |
Hyoscyamus niger |
? |
- |
? |
| 1.14.20.13 | norhyoscyamine + 2-oxoglutarate + O2 |
- |
Hyoscyamus niger |
6-hydroxynorhyoscyamine + succinate + CO2 + H2O |
- |
? |
| 1.14.20.13 | phenylacetyltropine + 2-oxoglutarate + O2 |
- |
Hyoscyamus niger |
6-hydroxyphenylacetyltropine + succinate + CO2 + H2O |
- |
? |
| 1.14.20.13 | t-cinnamoyltropine + 2-oxoglutarate + O2 |
- |
Hyoscyamus niger |
t-cinnamoyl-6-hydroxytropine + succinate + CO2 + H2O |
- |
? |
