EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.126 | oleanolic acid + [reduced NADPH-hemoprotein reductase] + O2 |
hydroxylation at C-16beta, reaction of EC 1.14.13.173 |
Platycodon grandiflorus |
cochalic acid + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | oleanolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Medicago truncatula |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | oleanolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Vitis vinifera |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | oleanolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Platycodon grandiflorus |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | oleanolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Glycyrrhiza uralensis |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | oleanolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Ocimum basilicum |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | oleanolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Glycyrrhiza uralensis 308-19 |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | ursolic aldehyde + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Glycyrrhiza uralensis |
ursolic acid + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | uvaol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Glycyrrhiza uralensis |
ursolic aldehyde + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 |
overall reaction |
Medicago truncatula |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
CYP716A12 mainly catalyzes the sequential three-step oxidation at the C-28 position necessary to transform beta-amyrin into oleanolic acid |
? |