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EC Number Source Tissue Commentary Reference
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270embryo - 286474
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270seedling - 286474
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270brain - 286475
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270hypothalamus - 286475
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270kidney - 286475
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270PC-3 cell AKR1C2 is not a source of 5alpha-dihydrotestosterone in PC-3 cells 655348
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270prostate in primary cultures of epithelial cells, high levels of AKR1C2 transcripts are detected in prostate cancer, but not in cell from normal prostate. In prostate cells AKR1C2 acts as a 3-ketosteroid reductase to eliminate 5alpha-dihydrotestosterone and prevents activation of androgen receptor 655348
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270prostate cancer cell in primary cultures of epithelial cells, high levels of AKR1C2 transcripts are detected in prostate cancer, but not in cell from normal prostate 655348
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270Hep-G2 cell HepG2 cells which lack 3-ketohydroxysteroid reductase/DELTA5-4ketosteroid isomerase mRNA expression, but express AKR1C1-AKR1C3 are able to convert 17beta-hydroxy-5alpha-androstan-3-one to 3beta-androstanediol and 3alpha-androstanediol 656200
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270embryo high expression levels in the ganglion of the trigeminal nerve and the dorsal root ganglia 656795
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