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EC Number
Source Tissue
Commentary
Reference
1.1.1.270
neuron
-
673822
1.1.1.270
NS0 cell
-
711300
1.1.1.270
PC-3 cell
AKR1C2 is not a source of 5alpha-dihydrotestosterone in PC-3 cells
655348
1.1.1.270
placenta
3beta-HSD1 is selectively expressed in human placenta, mammary glands and breast tumors in women
763397
1.1.1.270
placenta
selective expression of 3beta-HSD1
725813
1.1.1.270
prostate
in primary cultures of epithelial cells, high levels of AKR1C2 transcripts are detected in prostate cancer, but not in cell from normal prostate. In prostate cells AKR1C2 acts as a 3-ketosteroid reductase to eliminate 5alpha-dihydrotestosterone and prevents activation of androgen receptor
655348
1.1.1.270
prostate cancer cell
in primary cultures of epithelial cells, high levels of AKR1C2 transcripts are detected in prostate cancer, but not in cell from normal prostate
655348
1.1.1.270
renal cortex
-
724124
1.1.1.270
seedling
-
286474
1.1.1.270
small intestine
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724124
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