1.1.1.270	adrenal gland	-	724124	
1.1.1.270	brain	-	286475	
1.1.1.270	brain	adult, juvenile, and developing	673822	
1.1.1.270	breast cancer cell	17beta-HSD7 is amplified in primary and progressive breast cancer	763396	
1.1.1.270	breast cancer cell	3beta-HSD1 is selectively expressed in human placenta, mammary glands and breast tumors in women	763397	
1.1.1.270	breast cancer cell	expression of 3beta-hydroxysteroid dehydrogenase type 1 (HSD3B1) in breast cancer is associated with shorter recurrence-free survival, and genetic or pharmacologic inhibition of HSD3B1 reduced colony formation and xenograft growth	763404	
1.1.1.270	breast cancer cell	selective expression of 3beta-HSD1	725813	
1.1.1.270	colon	-	724124	
1.1.1.270	corpus luteum	cell culture	762607	
1.1.1.270	embryo	-	286474	
1.1.1.270	embryo	high expression levels in the ganglion of the trigeminal nerve and the dorsal root ganglia	656795	
1.1.1.270	ganglion	of the trigeminal nerve, dorsal root ganglia, cranial ganglia	656795	
1.1.1.270	Hep-G2 cell	-	675595	
1.1.1.270	Hep-G2 cell	HepG2 cells which lack 3-ketohydroxysteroid reductase/DELTA5-4ketosteroid isomerase mRNA expression, but express AKR1C1-AKR1C3 are able to convert 17beta-hydroxy-5alpha-androstan-3-one to 3beta-androstanediol and 3alpha-androstanediol	656200	
1.1.1.270	hepatocyte	primary cultured hepatocyte	741250	
1.1.1.270	hepatocyte	primary, time-dependent reduction of tibolone into 3beta- and 3alpha-hydroxytibolone was observed again in a 4:1 ratio	675595	
1.1.1.270	hypothalamus	-	286475	
1.1.1.270	kidney	-	286475	
1.1.1.270	liver	-	286472, 286473, 286478, 675595	
1.1.1.270	lung	-	724124	
1.1.1.270	mammary gland	3beta-HSD1 is selectively expressed in human placenta, mammary glands and breast tumors in women	763397	
1.1.1.270	mammary gland	selective expression of 3beta-HSD1	725813	
1.1.1.270	MCF-7 cell	-	763396	
1.1.1.270	MDA-MB-231 cell	-	763404	
1.1.1.270	additional information	isozymes 3beta-HSD1 and 3beta-HSD2 are encoded by two distinct genes which are expressed in a tissue-specific pattern	725813	
1.1.1.270	additional information	no differences in activity and localization between femal and male animals, except for the juvenile female slices which shows increased activity	673822	
1.1.1.270	additional information	specifically expressed in tissues that are involved in the pathogenesis of congenital cholesterol-deficiency disorders	656795	
1.1.1.270	additional information	the enzyme expression occurs in all rabbit tissues, although its expression levels in the renal cortex, adrenal gland, small intestine and colon are high	724124	
1.1.1.270	mycelium	-	726098	
1.1.1.270	neural tube	-	656795	
1.1.1.270	neuron	-	673822	
1.1.1.270	NS0 cell	-	711300	
1.1.1.270	PC-3 cell	AKR1C2 is not a source of 5alpha-dihydrotestosterone in PC-3 cells	655348	
1.1.1.270	placenta	3beta-HSD1 is selectively expressed in human placenta, mammary glands and breast tumors in women	763397	
1.1.1.270	placenta	selective expression of 3beta-HSD1	725813	
1.1.1.270	prostate	in primary cultures of epithelial cells, high levels of AKR1C2 transcripts are detected in prostate cancer, but not in cell from normal prostate. In prostate cells AKR1C2 acts as a 3-ketosteroid reductase to eliminate 5alpha-dihydrotestosterone and prevents activation of androgen receptor	655348	
1.1.1.270	prostate cancer cell	in primary cultures of epithelial cells, high levels of AKR1C2 transcripts are detected in prostate cancer, but not in cell from normal prostate	655348	
1.1.1.270	renal cortex	-	724124	
1.1.1.270	seedling	-	286474	
1.1.1.270	small intestine	-	724124	
1.1.1.270	tail bud	-	656795	
1.1.1.270	telencephalic song nucleus HVC	-	673822	
1.1.1.270	telencephalic song nucleus RA	-	673822