EC Number   |
General Information |
Reference |
|---|
   2.5.1.93 | evolution |
the phylogenetic tree shows that 4-hydroxybenzoate geranyltransferase (PGT) and 4-hydroxybenzoate polyprenyltransferase (PPT) belong to two different clades |
760235 |
| 2.5.1.93 | metabolism |
the enzyme catalyzes a key step in the geranyl diphosphate pathway for shikonins biosynthesis, and its couples the mevalonate and the diphosphate pathways, overview |
721942 |
| 2.5.1.93 | metabolism |
the enzyme plays an important role in the biosynthesis pathways of shikonin derivatives |
760235 |
| 2.5.1.93 | metabolism |
the reaction catalyzed by lePGT-1 plays as a competing pathway on two substrates of the Q8 synthesis pathway, namely at IPP and 4-hydroxybenzoate |
737898 |
| 2.5.1.93 | more |
LePGT1 is a model membrane-bound aromatic substrate prenyltransferase |
738205 |
| 2.5.1.93 | physiological function |
regulatory enzyme in the biosynthesis of shikonin |
706366 |
| 2.5.1.93 | physiological function |
the enzyme is involved in the biosynthesis of a red naphthoquinone pigment, shikonin |
738205 |
| 2.5.1.93 | physiological function |
the enzyme is part of a metabolic strategy to further controll the respiratory levels in CoQ8 biosynthesis-deficient Escherichia coli strains, this metabolic strategy can lead to fine-tuning of aerobic lactate accumulation. The lactate and acetate concentrations increase with increasing enzyme levels, as does the cell density, while glucose concentration decreases, overview |
737898 |
