EC Number   |
General Information |
Reference |
|---|
    2.5.1.16 | malfunction |
an enzyme-deficient strain is auxotrophic for polyamines, requires spermidine for growth in its insect vector form, and is adversely impacted in its ability to infect mice |
-, 722385 |
| 2.5.1.16 | malfunction |
deletion of SpeE does not affect flagellar formation, but induces clockwise rotation bias |
759788 |
| 2.5.1.16 | more |
homozygous overexpressing transgenic tomato plant lines show a high level of Md-SPDS1 mRNA expression and a 1.5 to 2fold increase in the levels of free spermidine in fruits compared to the wild-type plants. Analysis of pericarp-columella and metabolites in placenta tissues reveal distinct metabolic profiles between the wild-type and transgenic lines, particularly at the late ripening stages, phenotypes, overview. The transgenic tomato fruits also show an increase in carotenoid accumulation, especially in lycopene, and increased ethylene production compared to wild-type fruits. Genes responsible for lycopene biosynthesis, including phytoene synthase, phytoene desaturase, and deoxy-D-xylulose 5-phosphate synthase, are significantly up-regulated in ripe transgenic fruits, whereas genes involved in lycopene degradation, including lycopene-epsilon cyclase and lycopene beta cyclase, are downregulated in the transgenic fruits compared to the wild-type |
723048 |
| 2.5.1.16 | physiological function |
in vitro shoots of a transgenic European pear overexpressing apple spermidine synthase (MdSPDS1) and the wild-type are subjected to long-term stress for 0.03 mM AlCl3. SPDS expression level and spermidine titer of the transgenic line are substantially higher than those of wild-type when subjected to long-term Al stress. Transgenic line show showed higher tolerance to Al stress, and its ameliorated performance is closely correlated to polyamine accumulation, especially, to a higher spermidine titer chiefly via alleviating oxidative status as well as by affecting mineral element balance |
703469 |
| 2.5.1.16 | physiological function |
in zebrafish spermidine, but not spermine, is essential for early development, organogenesis and colour pattern formation |
758872 |
| 2.5.1.16 | more |
ligand docking modeling using the tertiary structure model, overview |
721733 |
| 2.5.1.16 | malfunction |
maternal loss of spermidine synthase leads to lethality and defects in pancreas development |
758872 |
| 2.5.1.16 | malfunction |
microarray experiments with a spermidine synthase, spermine oxidase mutant (DELTAspe3DELTAfms1) strain are performed to investigate the responsiveness of yeast genes to supplementation with spermidine or spermine. Expression analysis identified genes responsive to the addition of either excess spermidine or spermine compared to a control culture. Results from global gene expression profiling demonstrate a more major role for spermidine in modulating gene expression in yeast than spermine |
706926 |
| 2.5.1.16 | more |
overexpression of yeast spermidine synthase impacts ripening, senescence and decay symptoms in tomato. Constitutive expression of ySpdSyn enhances intracellular levels of Spd in the leaf, and transiently during fruit development, whereas E8-ySpdSyn expression leads to Spd accumulation early and transiently during fruit ripening. The ySpdSyn transgenic fruits have a longer shelf life, reduced shriveling and delayed decay symptom development in comparison with the wild-type fruits, crop maturity is delayed in a CaMV35S-ySpdSyn genotype, with fruits accumulating higher levels of the antioxidant lycopene. Notably, whole-plant senescence in the transgenic plants is also delayed compared with wild-type plants, phenotypes, overview |
723422 |
| 2.5.1.16 | physiological function |
PgSPD expression is slightly induced by mannitol and CuSO4. Salt, chilling, abscisic acid and jasmonic acid trigger a significant induction of PgSPD expression within 12-24 h post-treatment, especially PgSPD is prominently induced by salt (41.5fold) |
705641 |
