Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search General Information

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 64 > >>
download as CSV
download all results as CSV
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255malfunction Aenzyme knockdown significantly reduces dendritic extension in cultured Purkinje cells 703852
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255physiological function the ARD1-NAT1 complex has acetyltransferase activity against microtubules in dendrites and regulates dendritic arborization in neuronal cells 703852
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255malfunction reduced enzyme levels result in pleiotropic oogenesis defects including abnormal cyst encapsulation, desynchronized cystocyte division, disrupted nurse cell chromosome dispersion, and abnormal chorion patterning. Loss of Ard1 affects cell survival/proliferation and is lethal for the animal 719333
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255malfunction naa10 morphants display increased lethality, growth retardation and developmental abnormalities like bent axis, abnormal eyes and bent tails 735797
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255physiological function the enzyme is essential for normal development and viability of zebrafish 735797
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255physiological function enzyme variant ARD1131 has no influence on cyclin D1 expression and cell growth 736273
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255metabolism ARD1 variants have different effects on hypoxia-inducible factor-1alpha stability and acetylation 739977
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255physiological function the enzyme is involved in ribosome synthesis. Optimal NatA function is important to the cooperative function of Brx1 with Ebp2 in 60S ribosomal subunit biogenesis 740179
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255malfunction knockdown of acetyltransferase ARD1 significantly reduces the growth rate of human cancer cell lines. Furthermore, ARD1 knockdown induces apoptosis or sensitizes cells to drug induced apoptosis. Enzyme knockdown reduces the transcriptional activity of the beta-Catenin/TCF4 complex, downregulating cyclin D1 and thereby promoting G1-arrest and inhibition of cell proliferation of lung cancer cells 740340
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.255physiological function the enzyme acts in complex with the NATH protein and catalyzes cotranslational acetylation of protein N-termini 740340
Results 1 - 10 of 64 > >>
download as CSV
download all results as CSV