EC Number   |
Expression |
Reference |
|---|
    1.14.14.14 | down |
dexamethasone (100 nM) and vascular endothelial growth factor (5 ng/ml) decrease CYP19A1 mRNA levels, while having no effect on aromatase activity |
764239 |
| 1.14.14.14 | down |
hypoxia exposure for 4 weeks or treatment with N-ethylmaleimide causes significant decreases in hypothalamic AROM activity, brain AROM mRNA and protein expressions. Treatments with Nomega-nitro-L-arginine methyl ester or vitamin-E prevent the downregulation of hypothalamic AROM activity and mRNA levels in hypoxic fish |
764772 |
| 1.14.14.14 | down |
phosphodiesterase type-5 inhibitor tadalafil inhibits aromatase mRNA and protein expression leading to an increase in testosterone levels in the supernatants |
745452 |
| 1.14.14.14 | more |
Cyp19a expression is significantly lower at 52 days post-hatch at the male-producing temperature (19°C) and increases to similar levels as treatments at 13°C or 16°C at 66 days post-hatch. Expression levels later in juvenile development (66191 days post-hatch) largely decrease with fish size |
744946 |
| 1.14.14.14 | more |
CYP19A1 mRNA levels and aromatase activity in villous cytotrophoblast cells reach a maximum after about 48 h of culture |
764239 |
| 1.14.14.14 | more |
gene is expressed highly in the resting phase and gives the highest transcript abundance in the preparatory phase. Human chorionic gonadotropin administration stimulates the expression |
745022 |
| 1.14.14.14 | more |
hypothalamic aromatase levels increase two times during annual gonadal cycle, once in a fully gravid fish and then in a reproductively quiescent fish |
745062 |
| 1.14.14.14 | up |
expression is upregulated upon treatment with benzophenone-2, 4-phenylphenol, bisphenol A, bisphenol S, and n-butylparaben. Cells treated with DDT, methoxychlor, benzophenone-2,4-phenylphenol, bisphenol A, bisphenol S, and n-butylparaben, display significantly increased aromatase enzyme activity |
765383 |
| 1.14.14.14 | up |
forskolin (10 mM) and myristate acetate (1 mM) increases CYP19A1 mRNA levels by 1.8- and 1.6fold, respectively, as well as inducing aromatase catalytic activity |
764239 |
