EC Number   |
Reaction |
Reference |
|---|
   2.3.1.159 | 3 malonyl-CoA + N-methylanthraniloyl-CoA = 4 CoA + 1,3-dihydroxy-N-methylacridone + 3 CO2 + H2O |
Belongs to a superfamily of plant polyketide synthases. Has many similarities to chalcone and stilbene synthases |
- |
| 2.3.1.159 | 3 malonyl-CoA + N-methylanthraniloyl-CoA = 4 CoA + 1,3-dihydroxy-N-methylacridone + 3 CO2 + H2O |
the starter substrates for chalcone synthase or acridone synthase reaction are placed in different topographies in the active site pocket of the enzymes. Therefore conformational changes in the periphery beyond the active site cavity volumes determine the product formation and interconversion of enzymes by mutation of the active sites is insufficient |
676366 |
| 2.3.1.159 | 3 malonyl-CoA + N-methylanthraniloyl-CoA = 4 CoA + 1,3-dihydroxy-N-methylacridone + 3 CO2 + H2O |
two-step mechanism |
486401, 486402 |
