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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.91diagnostics the enzyme defined as an independent prognostic factor for the development of non-small cell lung cancer cells 743940
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.91medicine the enzyme may serve as a valuable target for therapeutic intervention in pulmonary carcinogenesis 743940
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.91medicine upregulation of hDUS2 is a relatively common feature of pulmonary carcinogenesis. Selective suppression of hDUS2 enzyme activity and/or inhibition of formation of the hDUS2-tRNA synthetase complex could be a promising therapeutic strategy for treatment of many lung cancers. Significant association between higher levels of hDUS2 in tumors and poorer prognosis of lung cancer patients 711663
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