EC Number |
Natural Substrates |
---|
1.14.11.33 | DNA-3-methylcytosine + 2-oxoglutarate + O2 |
- |
1.14.11.33 | DNA-3-methylthymine + 2-oxoglutarate + O2 |
- |
1.14.11.33 | DNA-4-methylcytosine + 2-oxoglutarate + O2 |
- |
1.14.11.33 | DNA-base-CH3 + 2-oxoglutarate + O2 |
- |
1.14.11.33 | DNA-tetrahydro-2-furfurylguanosine + 2-oxoglutarate + O2 |
- |
1.14.11.33 | double-stranded DNA-1-methyladenine + 2-oxoglutarate + O2 |
major substrate, AlkB demethylates DNA-1-methyladenine and DNA-3-methylcytosine with comparable efficiencies and has only a modest preference for a single-stranded DNA substrate over its double-stranded DNA counterpart |
1.14.11.33 | double-stranded DNA-3-methylcytosine + 2-oxoglutarate + O2 |
major substrate, AlkB demethylates DNA-1-methyladenine and DNA-3-methylcytosine with comparable efficiencies and has only a modest preference for a single-stranded DNA substrate over its double-stranded DNA counterpart |
1.14.11.33 | methylated double-stranded bacteriophage lambda + 2-oxoglutarate + O2 |
- |
1.14.11.33 | methylated RNA bacteriophage MS2 + 2-oxoglutarate + O2 |
isoform ABH3 reactivates methylated single-stranded RNA bacteriophage MS2 |
1.14.11.33 | more |
isoform ABH2 does not reactivate methylated RNA bacteriophage MS2 or methylated double-stranded bacteriophage lambda |