EC Number |
Localization |
GeneOntology No. |
Reference |
---|
7.4.2.14 | cell surface |
- |
GO:0009986 AmiGO QuickGO |
761023 |
7.4.2.14 | endoplasmic reticulum |
- |
GO:0005783 AmiGO QuickGO |
-, 760824, 761022, 761023 |
7.4.2.14 | endoplasmic reticulum membrane |
- |
GO:0005789 AmiGO QuickGO |
-, 761021, 761450, 761628, 761629, 761633, 761634, 761636, 761637, 761911, 761912, 762003, 762006, 762062, 762297, 762466 |
7.4.2.14 | endoplasmic reticulum membrane |
10 transmembrane helices for TAP1 and predicted 9-10 TMs for TAP2, membrane topology of TAP, overview |
GO:0005789 AmiGO QuickGO |
760660 |
7.4.2.14 | endoplasmic reticulum membrane |
TAP1 and TAP2 contain a hydrophobic domain with a tentative number of eight membrane-spanning segments. Location of PSF1 is in the ER membrane, with the hydrophilic ATP-binding fold facing the cytosol. Potential N-glycosylation sites likely to be exposed to the ER lumen are present in PSF1 at the positions 250, 279, and 302 but are missing in PSF2 |
GO:0005789 AmiGO QuickGO |
762296 |
7.4.2.14 | endoplasmic reticulum membrane |
TAP1 when expressed alone or with TAP2 is largely, if not exclusively, localized to the endoplasmic reticulum, confocal immunofluorescence microscopy. Immunofluorescence localization study of recombinant TAP in VV-TAP[112]-infected murine L929 cells |
GO:0005789 AmiGO QuickGO |
761417 |
7.4.2.14 | endoplasmic reticulum membrane |
the subunits both have 6-10 transmembrane segments containing the pore-forming and nucleotide-binding domains in addition to the C-terminal ATP-binding domain located in the cytoplasm |
GO:0005789 AmiGO QuickGO |
761252 |
7.4.2.14 | endoplasmic reticulum membrane |
transmembrane enzyme |
GO:0005789 AmiGO QuickGO |
761233 |
7.4.2.14 | endoplasmic reticulum membrane |
transmembrane enzyme, a cytoplasmic loop forms the peptide binding site |
GO:0005789 AmiGO QuickGO |
761635 |
7.4.2.14 | membrane |
10 transmembrane (TM) helices for TAP1 and predicted 9-10 TMs for TAP2, membrane topology of TAP, overview |
GO:0016020 AmiGO QuickGO |
760660 |