EC Number   |
Localization |
GeneOntology No. |
Reference  |
|---|
    1.11.1.8 | microsome |
- |
- |
439716, 439718, 439722, 671397, 765858 |
| 1.11.1.8 | membrane |
- |
GO:0016020 AmiGO QuickGO |
439721, 439726, 671592 |
| 1.11.1.8 | membrane |
integral membrane protein |
GO:0016020 AmiGO QuickGO |
439716, 439724, 673799 |
| 1.11.1.8 | apical part of cell |
in Graves disease, the nuclear envelope, enlarged rough endoplasmic reticulum, and apical vesicles are strongly TPO positive |
GO:0045177 AmiGO QuickGO |
658882 |
| 1.11.1.8 | microvillus |
of Graves disease thyroid, enzyme is absent in the microvilli in multinodular goiter |
GO:0005902 AmiGO QuickGO |
658882 |
| 1.11.1.8 | mitochondrion |
Hashimotos thyroiditis and oncocytic adenoma, are typically packed with mitochondria, display TPO reaction exclusivly in mitochondrial crisae |
GO:0005739 AmiGO QuickGO |
658882 |
| 1.11.1.8 | more |
in the perinodular normal tissue the enzyme is absent in the apical surface, enzyme from multinodular goiter is absent in the microvilli |
- |
658882 |
| 1.11.1.8 | nuclear envelope |
in the perinodular normal tissue the enzyme is detected mainly in the nuclear envelope, rough endoplasmic reticulum, and subapical vesicles. In cells from Hashimotos thyroiditis. In Graves disease, the nuclear envelope, enlarged rough endoplasmic reticulum, and apical vesicles are strongly TPO positive |
GO:0005635 AmiGO QuickGO |
658882 |
| 1.11.1.8 | rough endoplasmic reticulum |
in the perinodular normal tissue the enzyme is detected mainly in the nuclear envelope, rough endoplasmic reticulum, and subapical vesicles. In cells from Hashimotos thyroiditis detected in scarce rough endoplasmic reticulum. In Graves disease, the nuclear envelope, enlarged rough endoplasmic reticulum, and apical vesicles are strongly TPO positive |
GO:0005791 AmiGO QuickGO |
658882 |
| 1.11.1.8 | vesicle |
in Graves' disease, the nuclear envelope, enlarged rough endoplasmic reticulum, and apical vesicles are strongly TPO positive, in the perinodular normal tissue the enzyme is detected mainly in the nuclear envelope, rough endoplasmic reticulum, and subapical vesicles |
GO:0031982 AmiGO QuickGO |
658882 |
