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EC Number
Inhibitors
Commentary
Structure
1.1.1.40
(NH4)2SO4
at high concentrations
1.1.1.40
(S)-malate
substrate inhibition
1.1.1.40
(S)-malate
an increase to malate concentration of 10 mM decreases the specific activity of rHVME1 by almost 50%
1.1.1.40
(S)-malate
-
1.1.1.40
1-methylenecyclopropan-trans-2,3-dicarboxylic acid
-
1.1.1.40
1-methylenecyclopropane
inhibits at 10 mM
1.1.1.40
2'-AMP
competitive
1.1.1.40
2,3-Butanedione
pseudo-first-order loss of oxidative decarboxylase activity
1.1.1.40
2-Ketoglutarate
34% inhibition at 2 mM
1.1.1.40
2-mercaptoethanol
inactivation in absence of Mg2+
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