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EC Number
Inhibitors
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Structure
3.1.21.7
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an oligonucleotide duplex containing a 2'-fluorinated sugar moiety at the cyclobutane pyrimidine dimer (CPD) site inhibits the T4 Endo V reaction by stabilizing the covalent enzyme-DNA complex
3.1.21.7
NaCl
complete inhibition at 1 M
3.1.21.7
NaCl
200 mM, complete inhibition
3.1.21.7
NaCl
activity is suppressed by high NaCl concentration. When adding 500 mM NaCl in the cleavage reaction, the cleavage efficiency of the enzyme is reduced to be approximately 50%. At NaCl concentrations over 800 mM, only slight endonuclease activity remains
3.1.21.7
NaCl
above 100 mM, strong inhibition
3.1.21.7
NaCN
50% inhibition at 3-5 mM
3.1.21.7
tRNA
half-maximal inhibition rate at 0.08 mM
3.1.21.7
Zn2+
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