1.11.1.8 | arsenic trioxide |
0.1 ppm arsenic trioxide has no effect on TPO activity, incubation for 2 min in the presence of 1.0, 5.0, or 10 ppm arsenic trioxide inhibits TPO activity to 4%, 9%, and 9% of control, respectively. After 10 min incubation in the presence of 1.0 or 5.0 ppm arsenic trioxide, TPO activity returns to 92% and 54% of control, respectively, while the presence of 10 ppm arsenic trioxide further inhibits TPO activity to 1% of control |
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