EC Number   |
Activating Compound |
Reference  |
|---|
   1.4.1.3 | ADP |
activation only if concentrations of both NAD(P)+ and substrate are high |
391597 |
| 1.4.1.3 | Trypsin |
limited trypsin proteolyis activates the purified enzyme 8fold if the peptide is absent from the assay mixture, the native enzyme is 3fold activated if the cleaved peptide is present, activation may therefore be induced by loss of the peptide from the subunit of the native enzyme |
391598 |
| 1.4.1.3 | ADP |
above pH 7.0: allosteric activation |
391603 |
| 1.4.1.3 | ADP |
pH 6.0-7.0: strong inhibition |
391603 |
| 1.4.1.3 | GTP |
inhibition at pH 9.0, activation in presence of electrolytes at pH 6.0 |
391603 |
| 1.4.1.3 | phosphate |
activator at pH 8.0-9.0, inhibitor at pH 6.0-7.6 |
391603 |
| 1.4.1.3 | ADP |
stimulation |
391605, 391606, 391624, 391625 |
| 1.4.1.3 | AMP |
1 mM, reaction velocity increases 15fold at saturating NAD+ and glutamate levels |
391605 |
| 1.4.1.3 | 2-mercaptoethanol |
2fold activation |
391608 |
| 1.4.1.3 | glutathione |
2fold activation |
391608 |
