platelet alpha granuleGene ontology ID
GO:0031091
Definition
A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG)
Synonyms
1. platelet alpha-granule
References
1. PMID 84672332. Wikipedia: Platelet alpha-granule
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