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Gene ontology
Version 2014-12-22
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Details for SeqA-DNA complex
Gene ontology ID
GO:1990097
Definition
A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle
Synonyms
1. SeqA-dsDNA complex
2. SeqA-hemimethylated DNA complex
3. SeqA-hemimethylation dsDNA complex
References
1. GOC: bhm
2. PMID 12379844
3. PMID 15933720
4. PMID 23149570
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