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Version 2014-12-22
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Details for mitochondrial permeability transition pore complex
Gene ontology ID
GO:0005757
Definition
A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D)
Synonyms
1. mitochondrial PT pore complex
2. MPTP complex
3. PTPC
References
1. PMID 10393078
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