2.7.11.23Gene ontology ID
GO:0008353
Definition
Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats
Synonyms
1. [RNA-polymerase]-subunit kinase activity
2. ATP:DNA-directed RNA polymerase phosphotransferase activity
3. CTD kinase activity
4. RNA polymerase II carboxy-terminal domain kinase activity
5. RNA polymerase subunit kinase activity
6. RNA-polymerase-subunit kinase activity
7. STK9
References
1. EC 2.7.11.232. GOC: mah
3. MetaCyc RNA-POLYMERASE-SUBUNIT-KINASE-RXN4. Reactome: R-HSA-167191 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex"
5. Reactome: R-HSA-170704 "Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex"
6. Reactome: R-HSA-170706 "Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
/
/
at least 1 tissue/ enzyme/ localization link in this branch
/
/
tissue/ enzyme/ localization link to BRENDA