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Gene ontology
Version 2014-12-22
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Details for phospholipase C-inhibiting G protein-coupled receptor signaling pathway
Gene ontology ID
GO:0030845
Definition
A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG)
Comment
This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) inhibition.
Synonyms
1. G-protein-coupled inhibitory pathway of phospholipase C
2. GPCR signaling pathway coupled to inhibition of phospholipase C activity
3. GPCR signaling pathway via inhibition of PLC
4. inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway
5. phospholipase C inhibition
6. phospholipase C-inhibiting G-protein coupled receptor signaling pathway
7. PLC-inhibiting GPCR signaling pathway
References
1. GOC: dph
2. GOC: mah
3. GOC: signaling
4. GOC: tb
5. PMID 8280098
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