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Gene ontology
Version 2014-12-22
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Details for mRNA splicing, via endonucleolytic cleavage and ligation
Gene ontology ID
GO:0070054
Definition
Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons
Comment
Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
Synonyms
1. cytosolic mRNA splicing
References
1. GOC: krc
2. GOC: mah
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