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Literature summary for 7.4.2.8 extracted from

  • Paul, K.; Erhardt, M.; Hirano, T.; Blair, D.F.; Hughes, K.T.
    Energy source of flagellar type III secretion (2008), Nature, 451, 489-492.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information weak swarming motility and rare flagella are observed in a mutant deleted for FliI and for the nonflagellar type III secretion ATPases InvJ and SsaN Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Salmonella enterica FliI, an ATPase, provides the energy for export of the protein subunits, that form the filament and other structures to outside the membrane, via a specialized secretion apparatus, overview. This apparatus is related to the injectisome used by many gram-negative pathogens and symbionts to transfer effector proteins into host cells by type III secretion mechanism. Flagellar secretion in Salmonella enterica requires the proton motive force and does not require ATP hydrolysis by FliI. FliI is non-essential for flagellar assembly and function ADP + phosphate
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?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
Salmonella enterica ADP + phosphate
-
?
ATP + H2O FliI, an ATPase, provides the energy for export of the protein subunits, that form the filament and other structures to outside the membrane, via a specialized secretion apparatus, overview. This apparatus is related to the injectisome used by many gram-negative pathogens and symbionts to transfer effector proteins into host cells by type III secretion mechanism. Flagellar secretion in Salmonella enterica requires the proton motive force and does not require ATP hydrolysis by FliI. FliI is non-essential for flagellar assembly and function Salmonella enterica ADP + phosphate
-
?

Synonyms

Synonyms Comment Organism
FliI
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Salmonella enterica