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Information on EC 7.4.2.8 - protein-secreting ATPase

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IUBMB Comments
A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase that is involved in protein transport. There are several families of enzymes included here, e.g. ATP-hydrolysing enzymes of the general secretory pathway (Sec or Type II), of the virulence-related secretory pathway (Type III) and of the conjugal DNA-protein transfer pathway (Type IV). Type II enzymes occur in bacteria, archaea and eucarya, whereas type III and type IV enzymes occur in bacteria where they form components of a multi-subunit complex.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes
+
+
cellular protein[side 1]
=
+
+
cellular protein[side 2]
Synonyms
afGspE, BsaS, CdsN, Cpn0707, critical multidomain T2SS assembly ATPase, DotB, DotBL, DotBY, EivC, Eps, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + cellular protein[side 1] = ADP + phosphate + cellular protein[side 2]
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