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Literature summary for 7.4.2.8 extracted from

  • Sorg, J.A.; Blaylock, B.; Schneewind, O.
    Secretion signal recognition by YscN, the Yersinia type III secretion ATPase (2006), Proc. Natl. Acad. Sci. USA, 103, 16490-16495.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information fusion of YopR secretion substrate to dihydrofolate reductase results in binding to enzyme and blocking of the type III secretion pathway Yersinia enterocolitica

Organism

Organism UniProt Comment Textmining
Yersinia enterocolitica
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type III secretion ATPase
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
YopR/in + ATP + H2O eleven N-terminal amino acids of YopR sectretion substrate function as secretion signal required for binding to enzyme Yersinia enterocolitica YopR/out + ADP + phosphate
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