Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DL-cystathionine | strongly inhibited by DL-cystathionine | Streptococcus mutans | |
L-cysteine | moderately inhibited by L-cysteine | Streptococcus mutans | |
L-djenkolic acid | strongly inhibited by L-djenkolic acid | Streptococcus mutans | |
additional information | not inhibited by FeSO4, L-arginine, L-glutamine, L-glutamate, L-leucine, and L-methionine | Streptococcus mutans | |
S-methyl-L-cysteine | moderately inhibited by S-methyl-L-cysteine | Streptococcus mutans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + L-cystine-[cystine-binding protein](side 1) | Streptococcus mutans | - |
ADP + phosphate + L-cystine(side 2) + [cystine-binding protein](side 1) | - |
? | |
ATP + H2O + L-cystine-[cystine-binding protein](side 1) | Streptococcus mutans UA159 | - |
ADP + phosphate + L-cystine(side 2) + [cystine-binding protein](side 1) | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus mutans | - |
- |
- |
Streptococcus mutans UA159 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + L-cystine-[cystine-binding protein](side 1) | - |
Streptococcus mutans | ADP + phosphate + L-cystine(side 2) + [cystine-binding protein](side 1) | - |
? | |
ATP + H2O + L-cystine-[cystine-binding protein](side 1) | - |
Streptococcus mutans UA159 | ADP + phosphate + L-cystine(side 2) + [cystine-binding protein](side 1) | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cystine ABC transporter | - |
Streptococcus mutans |
TcyABC transporter | - |
Streptococcus mutans |
TcyB | - |
Streptococcus mutans |
Organism | Comment | Expression |
---|---|---|
Streptococcus mutans | the transcriptional regulator TcyR negatively regulates the expression of the enzyme | down |
Streptococcus mutans | enzyme expression is upregulated under cystine starvation and by the transcriptional activator CysR | up |