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Literature summary for 5.6.2.2 extracted from

  • Iida, A.; Kano, M.; Kubota, Y.; Koga, K.; Tomioka, K.
    Podophyllotoxin aza-analogue, a novel DNA topoisomerase II inhibitor (2000), Chem. Pharm. Bull., 48, 486-489.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
3-Methoxy-5-(6-oxo-5,8,8a,9-tetrahydro-1,3,7-trioxa-5a-aza-dicyclopenta[b,g]naphthalen-5-yl)-[1,2]benzoquinone inhibits decatenation, inhibition due to stabilization of the topoisomerase II-DNA covalent binary complex, the nonintercalative specific inhibitor stabilizes the cleavable complex Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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