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Literature summary for
5.6.2.2
extracted from
Peebles, K.A.; Baker, R.K.; Kurz, E.U.; Schneider, B.J.; Kroll, D.J.
Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum)
(2001),
Biochem. Pharmacol.
, 62, 1059-1070.
Search for more literature for 5.6.2.2
Inhibitors
Inhibitors
Comment
Organism
Structure
hypericin
inhibits DNA relaxation activity, potent antagonist of cleavage complex stabilization by chemotherapeutics etoposide and amsacrine
Homo sapiens
Organism
Organism
UniProt
Comment
Textmining
Homo sapiens
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