General Stability | Organism |
---|---|
enzyme in crude extract is stable to freezing and thawing | Clostridium sporogenes |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | in liver | Rattus norvegicus | 5829 | - |
mitochondrion | activity is 100fold lower than in cytosol of liver | Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-Leu | Homo sapiens | enzyme is involved in the synthesis of Leu from Val catabolites | ? | - |
? | |
beta-Leu | Rattus norvegicus | enzyme is involved in the synthesis of Leu from Val catabolites | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Andrographis paniculata | - |
- |
- |
Clostridium cochlearium | - |
- |
- |
Clostridium sporogenes | - |
- |
- |
Cyberlindnera jadinii | - |
- |
- |
Homo sapiens | - |
- |
- |
Lolium sp. | - |
- |
- |
Phaseolus vulgaris | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
skeletal muscle | high activity | Rattus norvegicus | - |
small intestine | very low activity | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-Leu | - |
Cyberlindnera jadinii | beta-Leu | - |
? | |
alpha-Leu | - |
Homo sapiens | beta-Leu | - |
? | |
alpha-Leu | - |
Rattus norvegicus | beta-Leu | - |
? | |
alpha-Leu | - |
Andrographis paniculata | beta-Leu | - |
? | |
alpha-Leu | - |
Clostridium cochlearium | beta-Leu | - |
? | |
alpha-Leu | - |
Lolium sp. | beta-Leu | - |
? | |
alpha-Leu | r | Phaseolus vulgaris | beta-Leu | - |
? | |
alpha-Leu | r | Clostridium sporogenes | beta-Leu | - |
? | |
beta-Leu | enzyme is involved in the synthesis of Leu from Val catabolites | Homo sapiens | ? | - |
? | |
beta-Leu | enzyme is involved in the synthesis of Leu from Val catabolites | Rattus norvegicus | ? | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
10 min stable, enzyme in crude extract | Clostridium sporogenes |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Cobalamin | not dependent on | Andrographis paniculata | |
cobamide | i.e. adenosylcobalamin, required | Clostridium sporogenes |