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Literature summary for 4.98.1.1 extracted from
- Isolation and functional characterization of mutant ferrochelatases in Saccharomyces cerevisiae (1996), Biochimie, 78, 144-152.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| G47S | thermosensitive phenotype | Saccharomyces cerevisiae |
| L62F | increase of Vmax and Km | Saccharomyces cerevisiae |
| S102F | thermosensitive phenotype | Saccharomyces cerevisiae |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | inner membrane | Saccharomyces cerevisiae | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protoporphyrin IX + Fe2+ | Saccharomyces cerevisiae | final step of heme biosynthesis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protoporphyrin + Fe2+ | - |
Saccharomyces cerevisiae | protoheme + 2 H+ | - |
? | |
| protoporphyrin IX + Fe2+ | final step of heme biosynthesis | Saccharomyces cerevisiae | ? | - |
? | |
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