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Information on EC 4.98.1.1 - protoporphyrin ferrochelatase

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EC Tree
     4 Lyases
         4.98 ATP-independent chelatases
             4.98.1 Forming coordination complexes
                4.98.1.1 protoporphyrin ferrochelatase
IUBMB Comments
The enzyme catalyses the terminal step in the heme biosynthesis pathways of eukaryotes and Gram-negative bacteria. The reaction is catalysed only in the reverse direction.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Synonyms
frataxin, ferrochelatase, heme synthetase, heme synthase, hem15, hemh1, hemh2, ppix ferrochelatase, protoporphyrin ix ferrochelatase, type ii ferrochelatase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
protoheme + 2 H+ = protoporphyrin + Fe2+
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