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Literature summary for 4.1.1.28 extracted from
- Constitutive aromatic L-amino acid decarboxylase from Micrococcus percitreus (1974), Biochem. Biophys. Res. Commun., 61, 75-82 .
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.4 | - |
L-tryptophan | at pH 9.0 and 30°C | Micrococcus percitreus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 101000 | - |
gel filtration | Micrococcus percitreus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan | Micrococcus percitreus | - |
tryptamine + CO2 | - |
? | |
| L-tryptophan | Micrococcus percitreus AJ 1065 | - |
tryptamine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Micrococcus percitreus | - |
- |
- |
| Micrococcus percitreus AJ 1065 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| protamine sulfate precipitation, ammonium sulfate precipitation, DEAE-Sephadex A-50 column chromatography, and Sephadex G-200 gel filtration | Micrococcus percitreus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-phenylalanine | 87% activity compared to L-tryptophan | Micrococcus percitreus | ? | - |
? | |
| L-phenylalanine | 87% activity compared to L-tryptophan | Micrococcus percitreus AJ 1065 | ? | - |
? | |
| L-tryptophan | - |
Micrococcus percitreus | tryptamine + CO2 | - |
? | |
| L-tryptophan | 100% activity | Micrococcus percitreus | tryptamine + CO2 | - |
? | |
| L-tryptophan | - |
Micrococcus percitreus AJ 1065 | tryptamine + CO2 | - |
? | |
| L-tryptophan | 100% activity | Micrococcus percitreus AJ 1065 | tryptamine + CO2 | - |
? | |
| L-tyrosine | 120% activity compared to L-tryptophan | Micrococcus percitreus | ? | - |
? | |
| L-tyrosine | 120% activity compared to L-tryptophan | Micrococcus percitreus AJ 1065 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Aromatic L-amino acid decarboxylase | - |
Micrococcus percitreus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Micrococcus percitreus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Micrococcus percitreus | |
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Release 2023.1 (January 2023)
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