Protein Variants | Comment | Organism |
---|---|---|
C221S | mutant catalytic activity on the burst phase is similar to that of the wild type BcII | Bacillus cereus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | metalloenzyme | Bacillus cereus | |
additional information | two metal ions are required for the hydrolytic activity of native zinc class B1 MBL BcII and highlight the importance of the Zn2 site during turnover | Bacillus cereus | |
Zn2+ | metalloenzyme, dependent, exist either as mononuclear or as dinuclear enzymes | Bacillus cereus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus cereus | P04190 | 569/H/9 | - |
Bacillus cereus 569/H/9 | P04190 | 569/H/9 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzylpenicillin + H2O | - |
Bacillus cereus | (2R,4S)-2-[(R)-carboxy(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
benzylpenicillin + H2O | - |
Bacillus cereus 569/H/9 | (2R,4S)-2-[(R)-carboxy(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
cefuroxime + H2O | - |
Bacillus cereus | (2R)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
cefuroxime + H2O | - |
Bacillus cereus 569/H/9 | (2R)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
apo Bacillus cereus 569/H/9 enzyme | metal-free BcII | Bacillus cereus |
BcII | - |
Bacillus cereus |
beta-lactamase | - |
Bacillus cereus |
metallo-beta-lactamase | - |
Bacillus cereus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Bacillus cereus |