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Literature summary for 3.4.24.B11 extracted from
- ADAMTS1 and ADAMTS5 metalloproteases produced by Sertoli cells a potential diagnostic marker in azoospermia (2019), Syst. Biol. Reprod. Med., 65, 29-38 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | ADAMTS1, ADAMTS5 and follicle stimulating hormone receptors are expressed 2.56, 2.10, and 2.66fold less in Sertoli cells of NOA patients, than those of obstructive azoospermia. After recombinant follicle stimulating hormone is added onto Sertoli cell cultures of patients with nonobstructive azoospermia, their expression does not increase significantly and does not reach to levels of control group. Expression of ADAMTS1 and ADAMTS5 are insignificantly 1.03 and 1.1fold higher in obstructive azoospermia group, respectively. In the nonobstructive azoospermia group, their expressions are 1.70 and 1.96fold lower, respectively, when compared with the fertile control | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9UHI8 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| semen | - |
Homo sapiens | - |
| Sertoli cell | - |
Homo sapiens | - |
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