Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
65000 | - |
SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
amyloid precursor protein + H2O | Rattus norvegicus | - |
fragments of amyloid precursor protein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
amyloid precursor protein + H2O | - |
Rattus norvegicus | fragments of amyloid precursor protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE1 | - |
Rattus norvegicus |
beta-secretase | - |
Rattus norvegicus |
beta-site amyloid precursor protein-cleaving enzyme | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | exacerbation of poststroke dementia by type 2 diabetes is associated with synergistic increases of beta-secretase activation, high fat diet-streptozotocin treatment increases the stroke-induced elevation of BACE1 expression and activity in the rat hippocampus. Middle cerebral artery occlusion-high fat diet-streptozotocin rats demonstrate an increase in BACE1 mRNA to 239.6% 24 h after ischemic operation compared with sham-normal pellet diet rats | up |