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Information on EC 3.4.23.46 - memapsin 2

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.46 memapsin 2
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein
Synonyms
bace1, gamma-secretase, presenilin 1, presenilin-1, alpha-secretase, bace-1, presenilin-2, bace 1, beta-site amyloid precursor protein cleaving enzyme, beta-site app-cleaving enzyme 1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein
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