Literature summary for 3.4.22.61 extracted from

Senft, J.; Helfer, B.; Frisch, S.M.
Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility (2007), Cancer Res., 67, 11505-11509.

Search for more literature for 3.4.22.61

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	stimulation of motility with epidermal growth factor induces the phosphorylation of caspase-8 on Tyr380. Caspase-8 phosphorylation converts it from a proapoptotic factor to a cell motility factor that, through Tyr380, interacts with p85, an established cell migration component	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
NB7 cell	caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility	Homo sapiens	-

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Release 2023.1 (January 2023)