Protein Variants | Comment | Organism |
---|---|---|
additional information | study on the effects of single-point amino acid substitutions on the structure and function of neuraminidase proteins. The rate of tolerant random one amino acid substitutions is 47%. Rates of tolerant substitutions for the stalk and for the surface and inner portion are 79%, 54%, and 19%, respectively. The ratio of mutations with which the enzyme loses neuraminidase activity, but is transported to the cell surface, decreases in proportion to the distance from the structural center of enzyme active site | influenza A virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
influenza A virus | - |
type H2N2 | - |
influenza A virus A/tokyo/3/67 | - |
type H2N2 | - |