Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.1.14 extracted from

  • Noh, M.Y.; Muthukrishnan, S.; Kramer, K.J.; Arakane, Y.
    A chitinase with two catalytic domains is required for organization of the cuticular extracellular matrix of a beetle (2018), PLoS Genet., 14, e1007307 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.14

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Hi-5 insect cells Tribolium castaneum

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Tribolium castaneum 5886
-

Organism

Organism UniProt Comment Textmining
Tribolium castaneum Q0Z942 red flour beetle
-

Source Tissue

Source Tissue Comment Organism Textmining
adult
-
 Tribolium castaneum
-
cuticle
-
 Tribolium castaneum
-
epidermis
-
 Tribolium castaneum
-
larva
-
 Tribolium castaneum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
carboxymethyl Remazol Brilliant Violet-chitin + H2O
-
 Tribolium castaneum ?
-
 ?

Subunits

Subunits Comment Organism
? x * 111000, calculated from amino acid sequence and SDS-PAGE Tribolium castaneum

Synonyms

Synonyms Comment Organism
CHT7
-
 Tribolium castaneum
endochitinase
-
 Tribolium castaneum

General Information

General Information Comment Organism
malfunction enzyme deficiency results in abnormal adult cuticle Tribolium castaneum
physiological function the enzyme is required for maintaining the integrity of the cuticle as a compact structure of alternating electron-dense and electron-lucent laminae. The enzyme is required for formation of properly oriented long chitin fibers inside pore canals that are vertically oriented columnar structures, which contribute to the mechanical strength of a lightweight, yet rigid, adult cuticle Tribolium castaneum