Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-([(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]amino)-N-(2,5-dimethylphenyl)acetamide | potent inhibitor with good selectivity against both placental and tissue-nonspecific alkaline phosphatase, competitive inhibition. A dose of 10 microM completley inhibits the enzyme expressed by transfected COS-1 cells | Mus musculus | |
N-(3-cyanophenyl)-3-([(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]amino)propanamide | potent inhibitor with good selectivity against both placental and tissue-nonspecific alkaline phosphatase | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P24822 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
duodenum | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
IAP | - |
Mus musculus |
intestinal-type alkaline phosphatase | - |
Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0032 | - |
2-([(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]amino)-N-(2,5-dimethylphenyl)acetamide | pH not specified in the publication, temperature not specified in the publication | Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00054 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | 2-([(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]amino)-N-(2,5-dimethylphenyl)acetamide | |
0.00182 | - |
pH not specified in the publication, temperature not specified in the publication | Mus musculus | N-(3-cyanophenyl)-3-([(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]amino)propanamide |