Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Al3+ | inhibits high molecular weight and low molecular weight alkaline phosphatase non-competitively | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
serum | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
high molecular weight alkaline phosphatase | - |
Rattus norvegicus |
low molecular weight alkaline phosphatase | - |
Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
high molecular weight alkaline phosphatase is less heat and urea stable than low molecular weight alkaline phosphatase | Rattus norvegicus |
additional information | - |
low molecular weight alkaline phosphatase is more heat and urea stable than high molecular weight alkaline phosphatase | Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | in vivo studies show that injection of AlCl3 in male rats results in decreased expression of brain and liver alkaline phosphatase. Gel filtration experiments disclose a high level of high molecular weight alkaline phosphatase compared to control animals | down |
Rattus norvegicus | in vivo studies show that injection of AlCl3 in male rats results in decreased expression of brain and liver alkaline phosphatase. Gel filtration studies show a significant reduction in low molecular weight alkaline phosphatase compared to control groups | down |
Rattus norvegicus | in vivo studies show that injection of AlCl3 in male rats results in an increased expression of serum alkaline phosphatase | up |