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Literature summary for 3.1.2.31 extracted from
- Finding the missing link in lovastatin biosynthesis LovG is the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover (2013), Angew. Chem. Int. Ed. Engl., 52, 6472-6475 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Aspergillus terreus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydromonacolin L-[lovastatin nonaketide synthase] + H2O | Aspergillus terreus | - |
holo-[lovastatin nonaketide synthase] + dihydromonacolin L acid | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus terreus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydromonacolin L-[lovastatin nonaketide synthase] + H2O | - |
Aspergillus terreus | holo-[lovastatin nonaketide synthase] + dihydromonacolin L acid | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LovG | - |
Aspergillus terreus |
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Release 2023.1 (January 2023)
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