Cloned (Comment) | Organism |
---|---|
transfection of HEK293-F cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | neither 8,11-eicosadiynoic acid nor 2-fluoropalmitic acid are selective or potent inhibitors of RPE65 | Homo sapiens | |
Triacsin C | inhibitor of fatty acyl:CoA ligases, potently inhibits RPE65 isomerase activity in cellulo, competitive inhibitor | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16518 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Rpe65 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0005 | - |
pH 8.0, 37°C | Homo sapiens | Triacsin C |
General Information | Comment | Organism |
---|---|---|
physiological function | RPE65 activity is reduced by coexpression of fatty acyl:CoA ligases or fatty acyl-CoA synthase FATP2 | Homo sapiens |