Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 3.1.1.64 - retinoid isomerohydrolase

for references in articles please use BRENDA:EC3.1.1.64
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.64 retinoid isomerohydrolase
IUBMB Comments
This enzyme, which operates in the retinal pigment epithelium (RPE), catalyses the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol, a key step in the regeneration of the visual chromophore in the vertebrate visual cycle . Interaction of the enzyme with the membrane is critical for its enzymic activity .
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
rpe65, isomerohydrolase, retinoid isomerase, retinoid isomerohydrolase, retinol isomerase, rpe65c, 13cimh, rpe65a, all-trans-reh, retinol isomerohydrolase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an all-trans-retinyl fatty acyl ester + H2O = 11-cis-retinol + a fatty acid
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.