Literature summary for 3.1.1.2 extracted from

Castellazzi, M.; Trentini, A.; Romani, A.; Valacchi, G.; Bellini, T.; Bonaccorsi, G.; Fainardi, E.; Cavicchio, C.; Passaro, A.; Zuliani, G.; Cervellati, C.
Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases (2016), Int. J. Biochem. Cell Biol., 81, 356-363 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood serum	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phenyl acetate + H2O	-	Homo sapiens	phenol + acetate	-	?

Expression

Organism	Comment	Expression
Homo sapiens	enzyme levels are significantly lower in patients affected by mild cognitive impairment, vascular dementia, late onset Alzheimer's disease, late onset Alzheimer's disease-vascular dementia mixed dementia as well as those with multiple sclerosis as compared to healthy controls	down

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Release 2023.1 (January 2023)