Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-benzyl-N-(2,3-dimethylphenyl)-3,5-dimethyl-1H-pyrazole-4-carboxamide | NIC04, in combination with NIC02, i.e. N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-4-methyl-2-phenyl-1,3-thiazole-5-carboximidic acid | Murine norovirus 1 | |
1H-benzimidazole-5-carboxylic acid, 2-[4-[[4'-chloro-4-(2-oxo-1-pyrrolidinyl)[1,1'-biphenyl]-2-yl]methoxy]-2-fluorophenyl]-1-cyclohexyl hydrochloride | i.e. JTK-109 | Murine norovirus 1 | |
2'-C-methylcytidine | - |
Murine norovirus 1 | |
8,8'-[carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) | i.e. NF023 | Murine norovirus 1 | |
favipiravir | - |
Murine norovirus 1 | |
N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-4-methyl-2-phenyl-1,3-thiazole-5-carboximidic acid | NIC02, in combination with NIC04, i.e. 1-benzyl-N-(2,3-dimethylphenyl)-3,5-dimethyl-1H-pyrazole-4-carboxamide | Murine norovirus 1 | |
suramin | - |
Murine norovirus 1 |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | Murine norovirus 1 | - |
diphosphate + RNAn+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Murine norovirus 1 | Q80J95 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | - |
Murine norovirus 1 | diphosphate + RNAn+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RDRP | - |
Murine norovirus 1 |
RNA-dependent RNA polymerase | - |
Murine norovirus 1 |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00007 | - |
pH and temperature not specified in the publication | Murine norovirus 1 | suramin | |
0.0002 | - |
pH and temperature not specified in the publication | Murine norovirus 1 | 8,8'-[carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) |