Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Yellow fever virus |
expression in Escherichia coli | West Nile virus |
expression in Escherichia coli | Japanese encephalitis virus |
expression in Escherichia coli | Zika virus |
expression in Escherichia coli | Dengue virus type 3 |
expression in Escherichia coli | Tick-borne encephalitis virus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
remdesivir triphosphate | remdesivir or its derivatives have the potential to become broad-spectrum antiviral agent effective against many RNA viruses | Dengue virus type 3 | |
remdesivir triphosphate | remdesivir or its derivatives have the potential to become broad-spectrum antiviral agent effective against many RNA viruses | Japanese encephalitis virus | |
remdesivir triphosphate | remdesivir or its derivatives have the potential to become broad-spectrum antiviral agent effective against many RNA viruses | Tick-borne encephalitis virus | |
remdesivir triphosphate | remdesivir or its derivatives have the potential to become broad-spectrum antiviral agent effective against many RNA viruses | West Nile virus | |
remdesivir triphosphate | remdesivir or its derivatives have the potential to become broad-spectrum antiviral agent effective against many RNA viruses | Yellow fever virus | |
remdesivir triphosphate | remdesivir or its derivatives have the potential to become broad-spectrum antiviral agent effective against many RNA viruses | Zika virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dengue virus type 3 | - |
- |
- |
Japanese encephalitis virus | - |
- |
- |
Tick-borne encephalitis virus | Q01299 | - |
- |
West Nile virus | - |
- |
- |
Yellow fever virus | - |
- |
- |
Zika virus | Q32ZE1 | genome polyprotein | - |
Purification (Comment) | Organism |
---|---|
- |
Yellow fever virus |
- |
West Nile virus |
- |
Japanese encephalitis virus |
- |
Zika virus |
- |
Dengue virus type 3 |
- |
Tick-borne encephalitis virus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNAn | - |
Yellow fever virus | diphosphate + RNAn+1 | - |
? | |
ATP + RNAn | - |
West Nile virus | diphosphate + RNAn+1 | - |
? | |
ATP + RNAn | - |
Japanese encephalitis virus | diphosphate + RNAn+1 | - |
? | |
ATP + RNAn | - |
Zika virus | diphosphate + RNAn+1 | - |
? | |
ATP + RNAn | - |
Dengue virus type 3 | diphosphate + RNAn+1 | - |
? | |
ATP + RNAn | - |
Tick-borne encephalitis virus | diphosphate + RNAn+1 | - |
? | |
CTP + RNAn | - |
Yellow fever virus | diphosphate + RNAn+1 | - |
? | |
CTP + RNAn | - |
West Nile virus | diphosphate + RNAn+1 | - |
? | |
CTP + RNAn | - |
Japanese encephalitis virus | diphosphate + RNAn+1 | - |
? | |
CTP + RNAn | - |
Zika virus | diphosphate + RNAn+1 | - |
? | |
CTP + RNAn | - |
Dengue virus type 3 | diphosphate + RNAn+1 | - |
? | |
CTP + RNAn | - |
Tick-borne encephalitis virus | diphosphate + RNAn+1 | - |
? | |
GTP + RNAn | - |
Yellow fever virus | diphosphate + RNAn+1 | - |
? | |
GTP + RNAn | - |
West Nile virus | diphosphate + RNAn+1 | - |
? | |
GTP + RNAn | - |
Japanese encephalitis virus | diphosphate + RNAn+1 | - |
? | |
GTP + RNAn | - |
Zika virus | diphosphate + RNAn+1 | - |
? | |
GTP + RNAn | - |
Dengue virus type 3 | diphosphate + RNAn+1 | - |
? | |
GTP + RNAn | - |
Tick-borne encephalitis virus | diphosphate + RNAn+1 | - |
? | |
UTP + RNAn | - |
Yellow fever virus | diphosphate + RNAn+1 | - |
? | |
UTP + RNAn | - |
West Nile virus | diphosphate + RNAn+1 | - |
? | |
UTP + RNAn | - |
Japanese encephalitis virus | diphosphate + RNAn+1 | - |
? | |
UTP + RNAn | - |
Zika virus | diphosphate + RNAn+1 | - |
? | |
UTP + RNAn | - |
Dengue virus type 3 | diphosphate + RNAn+1 | - |
? | |
UTP + RNAn | - |
Tick-borne encephalitis virus | diphosphate + RNAn+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NS5 | - |
Yellow fever virus |
NS5 | - |
West Nile virus |
NS5 | - |
Japanese encephalitis virus |
NS5 | - |
Zika virus |
NS5 | - |
Dengue virus type 3 |
NS5 | - |
Tick-borne encephalitis virus |
RDRP | - |
Yellow fever virus |
RDRP | - |
West Nile virus |
RDRP | - |
Japanese encephalitis virus |
RDRP | - |
Zika virus |
RDRP | - |
Dengue virus type 3 |
RDRP | - |
Tick-borne encephalitis virus |
RNA-dependent RNA polymerase | - |
Yellow fever virus |
RNA-dependent RNA polymerase | - |
West Nile virus |
RNA-dependent RNA polymerase | - |
Japanese encephalitis virus |
RNA-dependent RNA polymerase | - |
Zika virus |
RNA-dependent RNA polymerase | - |
Dengue virus type 3 |
RNA-dependent RNA polymerase | - |
Tick-borne encephalitis virus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00026 | - |
pH and temperature not specified in the publication | Yellow fever virus | remdesivir triphosphate | |
0.00101 | - |
pH and temperature not specified in the publication | Tick-borne encephalitis virus | remdesivir triphosphate | |
0.00136 | - |
pH and temperature not specified in the publication | Zika virus | remdesivir triphosphate | |
0.0014 | - |
pH and temperature not specified in the publication | Dengue virus type 3 | remdesivir triphosphate | |
0.00166 | - |
pH and temperature not specified in the publication | West Nile virus | remdesivir triphosphate | |
0.00214 | - |
pH and temperature not specified in the publication | Japanese encephalitis virus | remdesivir triphosphate |